Per-operative Angiography

Per-operative angiography is an advanced imaging technique used during surgery to provide real-time visualization of blood vessels and vascular structures. By injecting contrast agents, surgeons can closely examine the vascular system, a critical aspect of neurosurgical procedures, such as brain and spinal surgeries. This method enables accurate assessment of vascular anatomy, detection of abnormalities, and the ability to monitor blood flow throughout the operation, ensuring the safety and precision of surgical interventions.

The Role of Per-operative Angiography in Neurosurgery

In neurosurgery, per-operative angiography is indispensable, especially when dealing with complex vascular conditions like brain aneurysms, arteriovenous malformations (AVMs), vascular involvement in brain tumors, and spinal vascular anomalies. Its main role is to provide real-time insights into the vascular structure of the region being operated on, which helps surgeons visualize critical blood vessels, veins, and any abnormal vessels related to the pathology.

  • Assessment of Vascular Anatomy: Helps determine the precise location of arteries and veins, especially in areas where normal anatomical landmarks may be difficult to visualize.
  • Detection of Abnormal Vascular Structures: Identifies aneurysms, AVMs, or tumor-related blood vessels that may not be visible with traditional imaging techniques (such as CT or MRI).
  • Guiding Surgical Decision-making: Provides real-time feedback on how the surgical approach may affect blood flow, helping to prevent accidental damage to important blood vessels.
  • Ensuring Complete Treatment: In procedures such as aneurysm clipping or AVM resection, per-operative angiography helps ensure that the lesion has been completely treated and that there is no remaining abnormal blood flow.

Per-operative Angiography Techniques


Per-operative angiography involves the following techniques:

Digital Subtraction Angiography (DSA): This is the most widely used imaging technique for per-operative angiography. DSA provides high-resolution, real-time images of blood vessels, offering an excellent view of the vascular anatomy. During brain surgery, cerebral angiography is typically employed to visualize cerebral arteries and veins, with multiple images captured from different angles to ensure a comprehensive assessment of the vascular network in the affected area.

Angiography with Surgical Microscope: The surgical microscope is a tool that allows for detailed examination of microvascular structures. Microscope systems, especially in neurosurgery, provide a much higher resolution view of blood vessels and critical structures. Intraoperative angiography, combined with this high resolution, enables real-time visualization of blood vessels during surgical procedures.

Per-operative Angiography © ENI

Microscope-Assisted Angiography Application

When performing angiography with a surgical microscope, the high magnification and lighting capabilities enhance the detailed visualization of blood vessels. This method is crucial for accurately placing vascular structures, particularly in the brain and spinal cord. Microscope-assisted intraoperative angiography contributes to surgery in the following ways:

  • Higher Resolution Imaging: Surgical microscopes display the details of blood vessels with great clarity. Angiographic images clearly show the relationships between vessels, allowing the surgeon to visualize the operative field with greater precision.
  • Real-Time Imaging: Intraoperative angiography, when combined with the surgical microscope, allows the surgeon to observe real-time changes in the vascular structure during surgery, enhancing surgical accuracy.
  • Protection of Critical Blood Vessels: Especially in areas with cancerous tissue or vascular abnormalities, microscope-assisted intraoperative angiography helps prevent damage to critical blood vessels. The angiographic images allow the surgeon to precisely identify where the vessels are located and which ones need to be preserved.
  • Safer Interventions: Microscope-assisted visualization allows the surgeon to assess the effects of the intervention on the blood vessels with greater precision. Furthermore, the angiographic images confirm that the blood vessels are preserved and protected, enabling the surgeon to proceed with confidence.

Advantages of Per-operative Angiography

  1. Enhanced Visualization of Vascular Structures: Per-operative angiography provides unparalleled clarity and detail of brain vascular anatomy. This is crucial in complex cases involving intricate neural and vascular relationships, helping surgeons better understand the position of blood vessels relative to the lesion, minimizing risks during surgery.
  2. Real-time Monitoring: The ability to assess vascular structures during surgery allows surgeons to respond to changes in blood flow or other challenges in real time, leading to more accurate and precise interventions. This is particularly important when treating complex conditions like brain aneurysms or AVMs.
  3. Increased Surgical Precision: By visualizing blood flow during the procedure, per-operative angiography assists in performing more precise surgical maneuvers, reducing the risk of complications such as ischemia (reduced blood supply) or hemorrhage (bleeding).
  4. Reduced Need for Postoperative Intervention: By confirming the success of the surgery in real time, per-operative angiography reduces the need for additional interventions or reoperations, leading to quicker recovery and shorter hospital stays.
  5. Assessment of Tumor Vascularity: For neurosurgeons treating tumors, per-operative angiography is invaluable in assessing the vascular supply to the tumor and helps ensure complete resection without compromising nearby critical vessels. This helps prevent intraoperative bleeding and supports optimal tumor removal.
  6. Minimized Risk of Complications: One of the key advantages of per-operative angiography is its ability to minimize catastrophic complications such as inadvertent damage to major blood vessels. Real-time visualization of vascular structures allows surgeons to avoid or mitigate risks like hemorrhage or ischemia.
  7. Tailored Surgical Approaches: Surgeons can adjust their approach during surgery based on real-time data from the angiographic images, enabling more personalized and effective treatment plans. This is especially important in cases with abnormal vascular anatomy or high-risk lesions.
Content